De Novo Peptide Design
- Development of novel peptides with high affinity and selectivity for specific
protein domains through AI-assisted in silico library screening and structure-
based design strategies.
Related Publications:
- Chemical Engineering Journal, 2025, 522, 167447
- Chemical Science, 2023, 14, 9600-9607
Peptide Engineering
- Control of amino acid composition, macromolecular and folding structure,
and surface arrangement of peptides to enhance their structural and
functional properties.
Related Publications:
- Advanced Science 2022, 9(4), 2103098
- Advanced Functional Materials, 2018, 28(35), 1803114
Nanomedicine
- Multivalent protein binders/inhibitors and carrier-free drug delivery systems
for the treatment of diseases (e.g., cancer and sepsis), based on peptide-
nanoparticle conjugates and molecular self-assembly.
Related Publications:
- Biomacromolecules, 2023, 24(1), 141-149
- Journal of the American Chemical Society, 2020, 142(4), 1832-1837
Transdermal delivery
- Transdermal drug delivery using skin-penetrating peptide-based nanocarriers
for the treatment of dermatological diseases (e.g., skin cancer, alopecia, and
atopic dermatitis).
Related Publications:
- Advanced Functional Materials, 2025, 235(2), 2412160
- Biomacromolecules, 2024, 25(1), 436–443
Biosensor
- Development of rationally designed and modularly engineered peptide-based
receptors with superior target-detection capabilities compared to antibodies.
receptors with superior target-detection capabilities compared to antibodies.
Related Publications:
- Advanced Science, 2025, In press
- Biosensors and Bioelectronics, 2022, 213(1), 114445